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Monday, November 26, 2018

TASTE—IT’S THE STRUCTURE THAT COUNTS



Why do certain substances taste sweet, sour, bitter, or salty? Of course, it has to do with the taste buds on our tongues. But how do these taste buds work? For example, why does sugar taste sweet to us? The answer to this question remains elusive, but it does seem clear that sweet taste depends on how certain molecules fit the “sweet receptors” in our taste buds.

One of the mysteries of the sweet taste sensation is the wide variety of molecules that tastes sweet. The chemical structure of common table sugar (called sucrose) is shown on the right.
Sucrose

Sugar Cube
One artificial sweetener, aspartame, is used in many products including candy and diet soda. Some people are allergic to aspartame.
Aspartame

Another widely used artificial sweetener is sucralose which is made by modifying sucrose (compare the structure of sucralose to sucrose shown above). Look at the groups with blue circles in each structure. Sucralose is 600 times as sweet as sucrose and is used to sweeten beverages, baked goods, yogurt, and desserts.


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